The Jacksonville Jaguars have been underdogs in every game all season, and are unlikely to be favored in any games going forward. There is no change in that trend coming out of the bye week, as odds makers have the Titans favored by 12 points heading into Sunday.
Typically the Jaguars have been a solid team covering the spread, but on the season they're just 1-7 covering. The only spread the team has covered was the massive one against the Denver Broncos.
Conversely the Titans are 5-2-1 against the spread on the season, but the Jaguars should have a good chance of covering with two weeks to prepare for the matchup.
The over-under on the game opened at 41.5 according to OddsShark, which seems reasonable for the matchup given the two teams.