According to Vegas Insider, the Jaguars are as high as 10-point underdogs against the Indianapolis Colts this week. Ryan O'Halloran of the Florida Times-Union reported on Sunday that the Jaguars opened as 9.5-point underdogs, but that line has fluctuated between 8.5 and 10 points this week.
#Jaguars (1-2) installed as a 9 1/2-point underdog at Colts (1-2).— Ryan O'Halloran (@ryanohalloran) September 28, 2015
Julius Thomas is still likely out and Marqise Lee has two giant question marks as hamstrings (not to mention a defense missing nearly half its starters) so I'm surprised the Jaguars can be found for only 8.5-point underdogs in some places.
The over-under is between 47.0 and 47.5 points, which means that if Vegas is absolutely correct, the final score will be 28-19 in favor of the Colts.
I can't tell you that's not a very, very reasonable guess as to how Week 4 is going to end up for the Jaguars.