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Jacksonville Jaguars
| Pos. | Player | Injury | Wednesday | Thursday | Friday | Game Status |
| FB | Greg Jones | Hip | DNP | DNP | ||
| RB | Maurice Jones-Drew | Foot | DNP | DNP | ||
| DB | Dwight Lowery | Ankle | DNP | DNP | ||
| C | Brad Meester | Rest | DNP | DNP | ||
| FB | Montell Owens | Shoulder | DNP | Limited | ||
| CB | Rashean Mathis | Groin | Limited | DNP | ||
| CB | Derek Cox | Back | Limited | DNP | ||
| QB | Blaine Gabbert | Shoulder | Full | Full | ||
| WR | Laurent Robinson | Concussion | Full | Full |
Detroit Lions
| Pos. | Player | Injury | Wednesday | Thursday | Friday | Game Status |
| DE | Cliff Avril | Back | DNP | DNP | ||
| CB | Bill Bentley | Shoulder | DNP | To IR | --- | Out |
| S | Louis Delmas | Knee | DNP | DNP | ||
| WR | Calvin Johnson | Knee | DNP | DNP | ||
| RB | Mikel Leshoure | Not injured | DNP | --- | ||
| LB | DeAndre Levy | Hamstring | DNP | Limited | ||
| TE | Brandon Pettigrew | Knee | DNP | Limited | ||
| S | Amari Spievey | Concussion | DNP | DNP | ||
| DE | Kyle Vanden Bosch | Not injured | DNP | --- | ||
| DT | Corey Williams | Knee | DNP | Limited | ||
| LB | Justin Durant | Concussion | Limited | Limited | ||
| CB | Jacob Lacey | Concussion | Limited | Limited | ||
| LB | Stephen Tulloch | Knee | Limited | Limited | ||
| WR | Titus Young | Knee | Limited | Limited |
Practice Status key:
Full = Full participation in practice
Limited = Limited participation in practice
DNP = Did not participate in practice
IR = Placed on injured reserve
Game Status key:
Probable = 75% chance of playing
Questionable = 50% chance of playing
Doubtful = 25% chance of playing
Out = Will not play